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Skin Repair with Salmon: All About Beauty Clinic-Grade PDRN Skincare
From Medicine to Skincare: All About Korean PDRN Skincare
Skincare in recent years has gone beyond simple moisturising or wrinkle-smoothing effects to aim for full skin regeneration. And at the heart of this trend is the skin repairing hero ingredient from Korea – PDRN (Polydeoxyribonucleotide). Its powerful yet gentle rejuvenating and anti-aging abilities have elevated it to star status in the medical aesthetics and luxury skincare scenes. Want to achieve post-treatment bounce and plumpness at home? PDRN is just what you need.
What is PDRN?
PDRN is a low-molecular DNA fragment extracted from the sperm cells of salmon or trout (rainbow trout) that is 95-98% similar to human DNA. This high degree of biocompatibility grants PDRN with a powerful repair and cell regeneration capacity, which has been used to promote wound healing and tissue repair in the medical field long before the ingredient's emergence in the skincare scene.
With the recent popularity of medical aesthetics treatments like microneedling and injections, such as the widely known Korean aesthetics brand Rejuran, the application of PDRN on full-on cell regenerating skincare products has spread PDRN usage to the general public. And now – welcome to the age of the global PDRN skincare boom.
While known for its repairing prowess, PDRN's benefits for the skin are multifaceted and are ideal for mature, sensitive, and damaged skin alike:
Rapid Regeneration: Promotes Cell Division and Tissue Repair
Whether you're troubled by sunburn, acne breakout scars, or compromised post-treatment skin, PDRN can accelerate the recovery rate of epidermal cells to help fade scars and blemishes.
Firming and Anti-Aging: Stimulates Collagen and Elastin Proliferation
Radically lifts; improves fine lines, sagging, stretched and visible pores; and restores plumpness and softness.
Alleviating and Anti-inflammatory: Gentle and Relieving on Sensitive Skin
Helps inhibit inflammatory factors to soothe redness, acne inflammation, and post-treatment stings. Actual sensitive skin lifesaver.
Barrier Strengthening: Deep and Lasting Moisture
PDRN stimulates hyaluronic acid and ceramides metabolism to reduce water loss, strengthen the skin barrier, and improve dryness and flaking.
Brightening: Fades Blemishes and Pigmentation
Accelerates the repair of spots and acne marks for brighter and more even skin tone.
How to Choose Your PDRN: Salmon PDRN vs Vegan PDRN (Plant-based)
Given the growing diversity in skincare concepts and principles, vegan skincare and clean beauty have come into the spotlight. Similarly, PDRN can also be derived from vegan sources to support different lifestyle choices:
|
Type |
Source |
Benefits |
Who It's For |
|
Salmon PDRN |
Extracted from salmon or trout |
High biocompatibility with human body and excellent restorative properties. Widely used in aesthetics treatments and daily skincare. |
Most skin types; users seeking intense repair. |
|
Vegan/Plant-derived PDRN |
Extracted from plants such as ginseng |
Gentle, safe, hypoallergenic; compatible with vegan and eco-friendly lifestyles. |
Vegans/vegetarians; users with seafood allergies; extremely sensitive skin types. |
A variety of innovative trends and technological breakthroughs have placed PDRN at the centre of the K-beauty anti-aging skincare market, including its use in painless microneedling products, its plant-based vegan source, and the craze surrounding medical aesthetics treatments.
Now PDRN plays an integral role in our daily skincare routine, whether for anti-aging, soothing, illuminating, or repairing and hydrating effects. If you're looking for an all-around skin booster, keep reading for a comprehensive list of PDRN skincare products we recommend!
Best Korean PDRN Skincare Recommendations
Korean PDRN Face Serum Recommendation | HEVEBLUE Salmon Caring Centella Ampoule
At the heart of HEVEBLUE's flagship ampoule is the indulgent duo of salmon roe extract plus PDRN. This nourishing combo pours endless vitality into dry, rough, and fatigued skin. Prized by Korean users for its excellent calming effects, it has a pure and safe formula of high concentration centella asiatica and soothing botanicals good for dry sensitive skin and fragile, post-treatment skin.
Korean PDRN Face Serum Recommendation | Numbuzin No.2 Rose PDRN Collagen Plumping Serum
Find your skin growing sunken and saggy as you age? This numbuzin serum of 5% rose PDRN and high concentration collagen can help with that. The jelly-like collagen texture quickly replenishes collagen and fills fine lines, smooths wrinkles, and lifts your overall facial contour for a plumper, more youthful look. The addition of 5% niacinamide also leaves skin more radiant and complexion even. With a powerful duo of repairing plus brightening ingredients, this serum is your key to unlocking dewy Korean glass skin.
Korean PDRN Face Serum Recommendation | BIOHEAL BOH Probioderm Collagen Remodeling Booster Shot Program
Medical aesthetics treatment care with PDRN – right in the comfort of your home. This comprehensive 2-step set targets all key concerns of mature skin with a dual-ingredient microneedle formula of collagen and PDRN. Microneedling enables the ampoule to penetrate deeper and faster into skin to tighten pores, smooth fine lines and wrinkles, and brighten dull skin tone. Find your skin rejuvenated and glowing with hydration!
Korean PDRN Face Serum Recommendation | Rejuran Healer Turnover Ampoule Dual Effect
When it comes to PDRN, Rejuran has to be one of the first brands that spring to mind. It wouldn't be an exaggeration to call Rejuran the pioneer of PDRN; the brand has even been applauded by Korean users online to be 'microneedling without the needles'. This all-in-one bottle enhances skin's self-healing and regenerating abilities and boosts elasticity, firmness, and radiance. It gives you healthy, clarified, and luminous skin, as if after an aesthetics treatment – but without the pain and the needles!
Korean PDRN Face Serum Recommendation | Medicube PDRN Pink Exosome Shot Serum 2000
Fusing advanced exosome technology with high-purity salmon PDRN, collagen, 3 kinds of peptides and other potent ingredients, this serum is a trending ingredient dream team in a bottle. It delves deep into your skin with a microneedle formula that is 25 times smaller than pores to reduce blemishes, deeply rehydrate, restore elasticity, and turn back time for your skin both on the inside and out.
Korean PDRN Face Serum Recommendation | Medicube PDRN Pink Peptide Serum
If you have dull, blemished skin, reach for the Medicube PDRN peptide serum! The highly concentrated pink peptide and PDRN formula fills your skin with plumping collagen, and provides brightening, blemish-fading and elasticity-boosting benefits over 2 weeks of continuous use. The fresh, non-sticky texture and sensitive skin-friendly nature explains this serum's unwavering popularity and all its repurchases.
Korean PDRN Face Serum Recommendation | ANUA PDRN Hyaluronic Acid Capsule 100 Serum
At the heart of this plumping serum is the trending ingredient PDRN. The salmon-derived component promotes collagen production and improves skin elasticity, while a whopping 11 layers of hyaluronic acid and hydrolysed collagen help to hydrate and rejuvenate. Delivering hydration in a nourishing yet thin and weightless texture, it sinks into skin instantly and alleviates dryness from the very first drop, sending moisture to every layer of your skin.
Korean PDRN Face Serum Recommendation | VT PDRN Essence 100
This vegan-friendly essence from VT utilises plant-based PDRN extracted from 'mountain ginseng' for a milder, more stable formula compared to conventional PDRN. The creamy, emulsion-textured serum is also blended with plant oils and squalane to improve skin's moisture retention, besides brightening and repairing benefits. Skin is left sheer and smooth as glass.
Korean PDRN Moisturiser Recommendation | ANUA PDRN Hyaluronic Acid 100 Moisturizing Cream
A nourishing moisturiser for the colder seasons, this Anua face cream hydrates with three core ingredients: PDRN, 10 layers of hyaluronic acid, and hydrolysed collagen. It keeps every layer of your skin quenched while repairing and firming, giving your skin a full and hydrated look. The naturally green-tinted creamy texture is moisturising but not smothering. Free from artificial fragrances and pigments, it’s suitable for all skin types.
Korean PDRN Facial Mask Recommendation | Rejuran Healer Skin Protection Mask Sheet
Not quite ready to try the Rejuran injection treatment? Then be sure to try Rejuran in a sheet – the Healer Skin Protection Mask! The patented high-purity PDRN formula promotes skin regeneration and repairs damage. Offering intense hydration, it strengthens skin barrier defences against external stimuli. Enjoy medical-grade cosmetic effects from the comfort of your own home!
Korean PDRN Facial Mask Recommendation | Medicube PDRN Pink Collagen Gel Mask
The professional dermocosmetic skincare brand Medicube has jumped on the collagen gel mask bandwagon to launch masks concocted with not just PDRN but also pink peptides. Boosting hyaluronic and collagen synthesis, it leaves skin soft and bouncy and improves moisture retention for a rejuvenated and energised complexion.
Korean PDRN Facial Mask Recommendation | Medicube PDRN Pink Vita Coating Mask
99% high-purity salmon PDRN and pink vitamin serum – compressed into a snug-fitting sheet mask that seamlessly delivers nutrients to every inch of your skin. This collagen gel mask promotes collagen and hyaluronic acid production to repair and moisturise. It also offers blemish-fading benefits to return skin to a clarified and pristine state.
Korean PDRN Facial Mask Recommendation | VT PDRN Hydrogel Mask
VT's version of PDRN hydrogel masks is formulated with ginseng grown on Jirisan Mountain, South Korea, as well as squalane and a plant protein complex. Strengthening skin's natural defences, it improves your barrier's moisture retaining power and activates its self-repairing mechanism for double the anti-aging effect. Rejuvenate your skin with an aesthetics treatment-like experience at home and unveil revitalised, glowing, and bouncy skin under the mask.
Korean PDRN Facial Mask Recommendation | Anua PDRN 100 Hyaluronic Acid Glow Pad
Meet your secret weapon to glowing glass skin and hydrate, repair, and firm with just one pad! Each multifunctional pad drips with a rich formula of PDRN, hyaluronic acid, and peptides to fully combat inner dryness, improve skin elasticity, and impart a visible dewy glow.
Korean PDRN Eye Mask Recommendation | Abib PDRN Retinal Eye Patch Glow Jelly
Brightening and firming care for eye-area skin is the key to a youthful appearance! Featuring low-molecular vegan PDRN, Abib's pink jelly eye masks are packed with antioxidants that promote skin metabolism and support natural collagen growth to reduce dark circles and improve puffiness. Each embossed double-sided pad is slip-resistant and fits perfectly against the contours of the eyes, enabling the formula to penetrate deeply and restore radiance and vitality to eye-area skin.
Korean PDRN Lip Mask Recommendation | Abib PDRN Collagen Lip Mask Glazed Jelly
Spa-quality lip care – right at home! This plant-based PDRN and 3D Collagen Complex blend works alongside triple hyaluronic acid to instantly enrich dry, cracked lips. It fully fills and plumps lip wrinkles to reveal smooth, tender, texture-free lips. Slather a generous amount on lips before bed, enjoy intensive repair and continuous hydration as you sleep, and wake up to nourishment you can feel. This lip mask is an absolute must-have for dry lips, especially in the colder seasons.